PE-22-28

PE-22-28 10MG

Chemical Information

• Molecular Formula: C₃₅H₅₅N₁₁O₉
• Molecular Weight: 773.89 g/mol
• Sequence: GVSWGLR (Gly-Val-Ser-Trp-Gly-Leu-Arg)
• CAS Number: 1801959-12-5
• Description: Synthetic heptapeptide analog of Spadin (TREK-1 channel inhibitor)

Product Description PE-22-28 is a high-purity synthetic peptide supplied as a lyophilized white powder. This research compound is designed for in vitro and analytical research applications only, supporting laboratory studies involving TREK-1 potassium channel modulation, neuroprotection, mood regulation pathways, and antidepressant mechanism modeling.

This material is provided strictly for qualified laboratory environments and is not for human, animal, or therapeutic use.

Product Designation This product uses an internal catalog designation for identification and differentiation. It is not marketed or represented as any approved pharmaceutical or therapeutic compound.

Research Applications In controlled laboratory settings, PE-22-28 is used for:

• TREK-1 channel inhibition and neuronal excitability studies
• Neuroprotective and antidepressant-like mechanism research
• Investigation of mood disorder pathways and hippocampal function
• Comparative studies of Spadin analogs and potassium channel modulators
• Structural integrity, stability, and receptor interaction analysis
• Development and optimization of screening assays under experimental conditions

All applications are limited to non-human, non-clinical research models.

Storage and Handling

• Lyophilized form: Store at -20°C
• Reconstituted solution: Store at 2–8°C and use promptly
• Maintain aseptic techniques to preserve sterility and product integrity

Product Specifications

• Purity: ≥99% (HPLC Certified)
• Appearance: Lyophilized white powder
• Solubility: Soluble in standard laboratory buffers/solvents (e.g., sterile water or bacteriostatic water)

Important Compliance Notice This compound is FOR RESEARCH USE ONLY.

PE-22-28 is a synthetic peptide analog developed for laboratory investigation. This research material is not the investigational drug product, has not been evaluated by the FDA for any use, and is not intended for clinical, diagnostic, or veterinary applications.

Misuse of this product is strictly prohibited and may violate applicable laws. By purchasing, the buyer confirms that this product will be used exclusively for legitimate in vitro research purposes in qualified laboratory settings.

The Peptide Co. – Premium Research Peptides for Scientific Excellence. All products are sold for research purposes only. Not for human consumption.